SCIENTIFIC PROGRAMS AND ACTIVITIES
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Workshop on Adaptive Designs
September 25-27, 2003

Schedule

Thursday, September 25th
7:00 pm Welcome reception
Friday, September 26th
8:30 - 9:00 a.m.
Registration and Coffee
9:00 - 9:05 a.m. Welcome
9:05 - 9:50 a.m.
Nancy Flournoy (Missouri)
An Overview of Adaptive Designs
9:50 - 10:05 a.m. Break
10:05 - 10:55 a.m.
Yung-Pin Chen (Oregon)
Biased coin vs. Ehrenfest urn: an analysis of randomness, balance and power
10:55 - 11:10 a.m.
Break
11:10 - 12:00 p.m.
Tatsuki Koyama (Vanderbilt)
A calculus for design of two-stage adaptive procedures
12:00 - 2:00 p.m.
Lunch
2:00 - 2:50 p.m.
Subir Ghosh (California)
Adaptive factorial experiments for model identification
2:50 - 3:05 p.m
Break
3:05 - 3:55 p.m
Andre Rogatko (Fox Chase Cancer Center, Philadelphia)
Individualized patient dosing in phase I clinical trials
3:55 - 4:15 p.m. Break
4:15 - 4:35 p.m. Mourad Tighiouart (Fox Chase Cancer Center, Philadelphia)
Flexible Bayesian methods for cancer phase I clinical trials: dose escalation with overdose control
4:35 - 4:55 p.m. An-Lin Cheng (Georgia)
Minimum Hellinger distance estimation for randomized play the winner design
4:55 - 5:15 p.m Yevgen Tymofyeyev (Maryland)
Optimal Allocation in Multi-Armed Clinical Trials
6:30 p.m.
Banquet dinner
Saturday, September 27th
8:00 - 8:30 a.m. Morning Coffee
8:30 - 9:20 a.m.

Xikui Wang (Manitoba)
Bandit problems and adaptive clinical trials

9:20 - 9:30 a.m. Break
9:30 - 10:20 a.m.

Janis Hardwick (Michigan)
Optimal Few-Stage Designs for Clinical Trials
10:20 - 10:35 a.m.

Break
10:35 - 11:25 a.m.

Anand Vidyashankar (Georgia)
Nonparametric Likelihood for Response Adaptive Randomization with Delayed Response

11:25 - 11:40 a.m.

Break

11:40 - 12:30 p.m.

Anastasia Ivanova (UNC at Chapel Hill)
Response-adaptive designs: ethics and efficiency of estimation

12:30 - 2:10 p.m.

Lunch
2:10 - 3:00 p.m.

Hon Keung Tony Ng (Southern Methodist University, Dallas)
Up-and-down designs for phase I trials; an evaluation of different designs and estimators

3:00 - 3:15 p.m.

Break
3:15 - 4:05 p.m.

Feifang Hu (Virginia)
Response-adaptive designs: maximizing power and minimizing the expected number of failures

4:05 - 4:20 p.m.

Break
4:20 p.m.

Closing discussion of future directions